YDL223C (HBT1) gaosi pauta CAS No.: 489408-02-8 99% le mama maualalo mo mea faaopoopo

E fusifusia le HBT1 i le vaega e fusifusia ai le ligand o le α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) i se auala e faʻalagolago i le glutamate. O lona uiga o le HBT1 o se mole e naʻo se nofoaga patino i luga o le porotini AMPA-R e mafai ona fusifusia pe a iai le glutamate, ma o lenei fusifusia e fesoasoani e faʻatonutonu le gaioiga o le porotini. O loʻo faʻaalia AMPA receptors i le ogatotonu o le tino o neula ma e iai ni matafaioi taua i fesoʻotaʻiga neuronal, faʻagasologa o lagona, aʻoaʻoina, manatua, ma le synaptic plasticity. O AMPA receptors o ni mea taua e fesoasoani i le excitatory neurotransmission, e faʻatautaia vave, vave ona faʻaitiitia le lagona o le excitation i le tele o synapses, ma e aʻafia i tali vave i le glutamate i vaega synaptic. E masani ona faʻaalia faʻatasi AMPA receptors ma NMDA receptors i synapses, ma faʻatasi ai latou te faʻalauiloaina faiga synaptic plasticity e aʻafia i le aʻoaʻoina, manatua, excitotoxicity, ma le neuroprotection. O le Brain-derived neurotrophic factor (BDNF) o se neurotrophic factor e taua tele i le tausiga ma le faʻalauteleina o neurons ma e iai sona aafiaga malolosi ma tele i le faʻateleina, faʻavasegaina, ola ma le oti o neuronal ma non-neuronal cells. , o se neurotransmitter modulator e fesoasoani i le neuronal plasticity i le aʻoaʻoina ma le manatua. O le mea lea, e taua tele mo le soifua maloloina ma le manuia o le neula.