Palmitoylethanolamide (PEA) gaosi paʻu CAS Numera: 544-31-0 99% mama min. mo mea faaopoopo
Fua Fa'atatau
Igoa o oloa | PEA |
Isi igoa | N-(2-HYDROXYETHYL)HEXADECANAMIDE; N-HEXADECANOYLETHANOLAMINE; PEAPALMIDROL; PALMITYLETHANOLAMIDE; PALMITOYLETHChemicalbookANOLAMIDE |
CAS Nu. | 544-31-0 |
fua mole | C18H37NO2 |
mamafa mole | 299.49 |
mama | 99.0% |
Fa'aaliga | Pa'epa'e tioata pa'epa'e |
afifiina | 25Kg/ pa'u |
Fa'atatauga | Mea mata o oloa tau soifua maloloina |
Folasaga o oloa
Palmitoylethanolamide o se lipid avefe'au mole na maua muamua i le tuai o 1950s. E a'afia i le vasega o fa'apotopotoga e ta'ua o le endocannabinoids, o mea masani ia e fegalegaleai ma le tino endocannabinoid system. E le pei o isi cannabinoids e pei o le THC o loʻo maua i le cannabis laau, PEA e le o le mafaufau ma e le maua ai ni aʻafiaga e suia ai le mafaufau. O le endocannabinoid system (ECS) o se fesoʻotaʻiga lavelave o talitali ma endocannabinoids o loʻo maua i le tino atoa. E faia se sao taua i le faʻatonutonuina o le tele o faʻagasologa o le physiological, e aofia ai le lagona o le tiga, mumū, ma lagona. O le PEA o loʻo avea o se ligand faʻamaʻi mo se tali faʻapitoa i totonu o le ECS e taʻua o le peroxisome proliferator-activated receptor-α (PPAR-α). E ala i le faʻagaoioia o lenei tali, e faʻaaogaina e le PEA ona aʻafiaga faʻamaʻi ma analgesic. O suʻesuʻega e faʻaalia ai e mafai e Palmitoylethanolamide ona fesoasoani i le puleaina o tiga tumau, e aofia ai le neuropathic ma le tiga tiga. E galue e ala i le faʻaitiitia o le tuʻuina atu o mea faʻamaʻi faʻamaʻi ma faʻatonutonu le faʻagaoioia o sela puipuia o loʻo aʻafia i le tali inflammatory. O le tele o faʻataʻitaʻiga faʻataʻitaʻiga ua faʻaalia ai le aoga o le PEA i le faʻaitiitia o le tiga ma le faʻaleleia o le lelei o le olaga i tagata mamaʻi ma le tele o faʻamaʻi tiga masani.
Fa'aaliga
(1) Maualuga maualuga: E mafai e le PEA ona maua ni oloa mama maualuga e ala i le faʻamamaina o gaioiga gaosiga. O le mama maualuga o lona uiga e sili atu le bioavailability ma faʻaitiitia ai faʻalavelave leaga.
(2) Saogalemu: Saogalemu maualuga, nai mea leaga.
(3) Faʻamautu: O le PEA o loʻo i ai le mautu lelei ma e mafai ona faʻatumauina lana gaioiga ma aʻafiaga i lalo o siosiomaga eseese ma tulaga teuina.
Talosaga
Faʻaaogaina e fai ma faʻaopoopoga meaʻai, Palmitoylethanolamide o se gaʻo gaʻo amide faʻapitoa lea e faʻaaogaina ai le anti-inflammatory, analgesic, ma neuroprotective aʻafiaga e ala i le faʻaogaina o le endocannabinoid system. O ona aoga aoga mo le puleaina o tiga tumau ma isi tulaga faʻalesoifua maloloina e avea o se filifiliga manaia mo tagata taʻitoʻatasi o loʻo sailia ni auala masani. E le gata i lea, o le PEA foi o se vailaʻau faʻasolosolo faʻatasi ma vailaʻau vavalo, lea e mafai ona faʻaaogaina i suʻesuʻega suʻesuʻe ma atinaʻe faʻagasologa ma suʻesuʻega vailaʻau vailaʻau ma atinaʻe.