Nefiracetam pa'u gaosi oloa CAS Numera: 77191-36-7 99% mama min. mo mea faaopoopo
Vitio oloa
Fua Fa'atatau
| Igoa o oloa | Nefiracetam |
| Isi igoa | n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaceticacid,2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl) -N-(2,6-dimethylphenyl) -acetamide); DMMPA |
| CAS Nu. | 77191-36-7 |
| fua mole | C14H18N2O2 |
| mamafa mole | 246.3 |
| mama | 99.0% |
| Fa'aaliga | Pa'epa'e pa'epa'e |
| afifiina | 25 kilokalama/paila |
| Fa'atatauga | nootropic |
Folasaga o oloa
O le Nefiracetam e a'afia i le aiga o le piracetam, o se vasega o vaila'au e iloa mo a latou mea e fa'aleleia ai le mafaufau. Nefiracetam na muamua faʻapipiʻiina i le amataga o le 1980s ma vave ona tosina atu i ai ona o lona tulaga faʻapitoa o gaioiga ma faʻaoga togafitiga faʻapitoa. O lenei fa'aputuga o le racemic e manatu e a'afia ai neurotransmitters ma tali i totonu o le fai'ai, ma iu ai ina fa'alauteleina le fa'aleleia atili o le mafaufau. O le Nefiracetam e aʻafia ai le maualuga o le faiʻai o le acetylcholine, o se neurotransmitter autu e nafa ma le mafaufau, aʻoaʻoga, ma le gaioiga o le mafaufau. E ala i le faʻaogaina o le acetylcholine receptors, o le nefiracetam e faʻalauteleina ai fesoʻotaʻiga i le va o neu, ma faʻaleleia ai le synaptic plasticity ma faʻaleleia le taofiga manatua. E le gata i lea, o le nefiracetam e fegalegaleai ma gamma-aminobutyric acid (GABA) faʻafeiloaʻi e fesoasoani e faapaleni le neurotransmitter milieu. E ala i le aʻafia lelei o neurotransmitters excitatory ma inhibitory, nefiracetam fesoasoani e faʻamautu le lelei o le faiʻai, faʻaleleia atili le taulaʻi, gauai, ma le faʻatinoga o le mafaufau atoa.
Fa'aaliga
(1) Mamalu maualuga: E mafai e le Nefiracetam ona maua ni oloa mama maualuga e ala i le faʻamamaina o gaioiga gaosiga. O le mama maualuga o lona uiga e sili atu le bioavailability ma faʻaitiitia ai faʻalavelave leaga.
(2) Saogalemu: Saogalemu maualuga, nai mea leaga.
(3) Faʻamautu: Nefiracetam e lelei le mautu ma e mafai ona faʻatumauina lana gaioiga ma aʻafiaga i lalo o siosiomaga eseese ma tulaga teuina.
Talosaga
O le Nefiracetam o se mea e maua mai i le hydrophobic o le piracetam, lea e masani ona manatu o se vailaʻau e nafa ma le mauaina o ala o le calcium i totonu o le tino ma le faʻafeiloaʻi tuusaʻo o mea faʻailo faʻamalosi e avea o se vaega agonist o ala o le calcium ion. Glycine saisai nofoaga o le NDMA receptor. E ala i lona aʻafiaga i le cerebral cortex, e mafai e le nefiracetam ona faʻaleleia tomai faʻapitoa ma puipuia ai le aʻoaʻoina ma le faʻaleagaina o mafaufauga. E leai ni mea e maua ai le muscarinic receptor agonist poʻo ni mea faʻalavelave, e le taofia foi le gaioiga o le acetylcholinease. O le mea lea, o ona aafiaga anti-amnestic ma manatua-faʻaleleia e ausia e ala i le faʻaleleia o le tuʻuina atu o le acetylcholine i le cerebral cortex.
